ABL_family

Retrovirus-associated DNA sequences (abl) originally isolated from the Abelson murine leukemia virus (Ab-MuLV). The proto-oncogene abl (c-abl) codes for a protein that is a member of the tyrosine kinase family. The human c-abl gene is located at 9q34.1 on the long arm of chromosome 9. It is activated by translocation to bcr on chromosome 22 in chronic myelogenous leukemia. (mesh:D016313)

Cross-references

• MESH:D016313 - Genes, abl
• RE:R-HSA-376002
• IP:IPR015015
• MEDSCAN:urn:agi-aopfc:0000567

Synonyms

Synonym	Reference	Specificity
ABL		Exact
ABL family		Exact

Incoming Relations

Identifier	Name	Relation
HGNC:77	ABL2	isa
HGNC:76	ABL1	isa

Outgoing Relations

None available.