ADRA

Cell-surface proteins that bind epinephrine and/or norepinephrine with high affinity and trigger intracellular changes. The two major classes of adrenergic receptors, alpha and beta, were originally discriminated based on their cellular actions but now are distinguished by their relative affinity for characteristic synthetic ligands. Adrenergic receptors may also be classified according to the subtypes of G-proteins with which they bind; this scheme does not respect the alpha-beta distinction. (mesh:D011941)

Cross-references

• GO:GO:0004937 - alpha1-adrenergic receptor activity
• BEL:ADRA Family
• SFAM:F0010
• MESH:D011941 - Receptors, Adrenergic
• GO:GO:0004936 - alpha-adrenergic receptor activity

Synonyms

Synonym	Reference	Specificity
a-adrenoreceptor		Exact
α-adrenergic receptor		Exact
alpha-adrenoreceptors		Exact
α-adrenoreceptor		Exact
alpha1 adrenoceptor		Exact
alpha-adrenergic receptor		Exact
α-adrenoreceptors		Exact
alpha adrenoceptor		Exact
alpha-adrenoreceptor		Exact

Incoming Relations

Identifier	Name	Relation
HGNC:280	ADRA1D	isa
HGNC:283	ADRA2C	isa
HGNC:277	ADRA1A	isa
HGNC:281	ADRA2A	isa
HGNC:282	ADRA2B	isa
HGNC:278	ADRA1B	isa

Outgoing Relations

None available.