A family of transmembrane proteins that function primarily as calcium-activated chloride channels. Structurally, they form a homodimer where each subunit consists of eight transmembrane helices with the N and C terminals exposed to the cytosol. The regions between helices 5 and 7 may be important for ion pore formation and calcium ion binding. (mesh:D000075368)
Identifier | Name | Relation |
HGNC:21625 | ANO1 | isa |
HGNC:31677 | ANO7 | isa |
HGNC:20679 | ANO9 | isa |
HGNC:29329 | ANO8 | isa |
HGNC:25519 | ANO10 | isa |
HGNC:23837 | ANO4 | isa |
HGNC:14004 | ANO3 | isa |
HGNC:25240 | ANO6 | isa |
HGNC:1183 | ANO2 | isa |
HGNC:27337 | ANO5 | isa |
Relation | Identifier | Name |
isa | FPLX:Chloride_calcium_activated_channels | Chloride_calcium_activated_channels |