AP1

A multiprotein complex composed of the products of c-jun and c-fos proto-oncogenes. These proteins must dimerize in order to bind to the AP-1 recognition site, also known as the TPA-responsive element (TRE). AP-1 controls both basal and inducible transcription of several genes. (mesh:D018808)

Cross-references

• SCOMP:C0003
• BEL:AP-1 Complex
• NCIT:C17450
• MESH:D018808 - Transcription Factor AP-1

Synonyms

Synonym	Reference	Specificity
AP1		Exact
AP-1		Exact

Incoming Relations

Identifier	Name	Relation
FPLX:JUN_family	JUN_family	partof
FPLX:FOS_family	FOS_family	partof

Outgoing Relations

None available.