CDKN

A group of cell cycle proteins that negatively regulate the activity of CYCLIN/CYCLIN-DEPENDENT KINASE complexes. They inhibit CELL CYCLE progression and help control CELL PROLIFERATION following GENOTOXIC STRESS as well as during CELL DIFFERENTIATION. (mesh:D050756)

Cross-references

• MESH:D050756 - Cyclin-Dependent Kinase Inhibitor Proteins
• PF:PF02234
• NCIT:C18492

Synonyms

Synonym	Reference	Specificity
CKIs		Exact
cyclin-dependent protein kinase inhibitors		Exact
CDKN		Exact
cyclin dependent kinase inhibitors		Exact
cyclin-dependent kinase inhibitor		Exact

Incoming Relations

Identifier	Name	Relation
FPLX:CDKN1	CDKN1	isa
HGNC:1791	CDKN3	isa
FPLX:CDKN2	CDKN2	isa

Outgoing Relations

None available.