COX

A multisubunit enzyme complex containing CYTOCHROME A GROUP; CYTOCHROME A3; two copper atoms; and 13 different protein subunits. It is the terminal oxidase complex of the RESPIRATORY CHAIN and collects electrons that are transferred from the reduced CYTOCHROME C GROUP and donates them to molecular OXYGEN, which is then reduced to water. The redox reaction is simultaneously coupled to the transport of PROTONS across the inner mitochondrial membrane. (mesh:D003576)

Cross-references

Synonyms

Synonym Reference Specificity
Complex IV Exact
cytochrome c oxidase Exact

Incoming Relations

Identifier Name Relation
HGNC:2285 COX6C partof
HGNC:2292 COX7C partof
HGNC:2269 COX5B partof
FPLX:COX7B COX7B partof
FPLX:COX8 COX8 partof
HGNC:7419 MT-CO1 partof
HGNC:7422 MT-CO3 partof
FPLX:COX7A COX7A partof
HGNC:7421 MT-CO2 partof
FPLX:COX6B COX6B partof
FPLX:COX6A COX6A partof
HGNC:2267 COX5A partof
FPLX:COX4 COX4 partof

Outgoing Relations

None available.