E2F

A family of basic helix-loop-helix transcription factors that control expression of a variety of GENES involved in CELL CYCLE regulation. E2F transcription factors typically form heterodimeric complexes with TRANSCRIPTION FACTOR DP1 or transcription factor DP2, and they have N-terminal DNA binding and dimerization domains. E2F transcription factors can act as mediators of transcriptional repression or transcriptional activation. (mesh:D050684)

Cross-references

• MEDSCAN:urn:agi-complex:prophash-40bc2e4348830d6f7bdacd573fd7c388
• SFAM:F0070
• MESH:D050684 - E2F Transcription Factors
• BEL:E2F Family
• MEDSCAN:urn:agi-aopfc:0000099
• IP:IPR015633

Synonyms

Synonym	Reference	Specificity
E2F		Exact

Incoming Relations

Identifier	Name	Relation
HGNC:24727	E2F8	isa
HGNC:3114	E2F2	isa
HGNC:23820	E2F7	isa
HGNC:3113	E2F1	isa
HGNC:3115	E2F3	isa
HGNC:3118	E2F4	isa
HGNC:3119	E2F5	isa
HGNC:3120	E2F6	isa

Outgoing Relations

None available.