A family of basic helix-loop-helix transcription factors that control expression of a variety of GENES involved in CELL CYCLE regulation. E2F transcription factors typically form heterodimeric complexes with TRANSCRIPTION FACTOR DP1 or transcription factor DP2, and they have N-terminal DNA binding and dimerization domains. E2F transcription factors can act as mediators of transcriptional repression or transcriptional activation. (mesh:D050684)



Synonym Reference Specificity
E2F Exact

Incoming Relations

Identifier Name Relation
HGNC:3118 E2F4 isa
HGNC:3114 E2F2 isa
HGNC:3120 E2F6 isa
HGNC:23820 E2F7 isa
HGNC:3113 E2F1 isa
HGNC:3119 E2F5 isa
HGNC:3115 E2F3 isa
HGNC:24727 E2F8 isa

Outgoing Relations

None available.