EGFR_ligand

A family of proteins that are related to epidermal growth factor. They share in common a consensus sequence consisting of six spatially conserved CYSTEINE residues which form three intramolecular bonds. This consensus sequence is commonly referred to EGF motif and is considered essential for binding of the proteins to ERB RECEPTORS. (mesh:D066255)

Cross-references

• BEL:EGFR Ligand Family
• SFAM:F0072
• MESH:D066255 - EGF Family of Proteins
• GO:GO:0005154 - epidermal growth factor receptor binding

Synonyms

Synonym	Reference	Specificity
EGFR ligands		Exact
EGFR ligand		Exact

Incoming Relations

Identifier	Name	Relation
HGNC:3229	EGF	isa
HGNC:3443	EREG	isa
HGNC:3059	HBEGF	isa
HGNC:17470	EPGN	isa
HGNC:651	AREG	isa
HGNC:1121	BTC	isa
HGNC:11765	TGFA	isa

Outgoing Relations

None available.