A family of proteins that are related to epidermal growth factor. They share in common a consensus sequence consisting of six spatially conserved CYSTEINE residues which form three intramolecular bonds. This consensus sequence is commonly referred to EGF motif and is considered essential for binding of the proteins to ERB RECEPTORS. (mesh:D066255)



Synonym Reference Specificity
EGFR ligands Exact
EGFR ligand Exact

Incoming Relations

Identifier Name Relation
HGNC:3229 EGF isa
HGNC:651 AREG isa
HGNC:11765 TGFA isa
HGNC:3059 HBEGF isa
HGNC:17470 EPGN isa
HGNC:1121 BTC isa
HGNC:3443 EREG isa

Outgoing Relations

None available.