A hydro-lyase that catalyzes the dehydration of 2-phosphoglycerate to form PHOSPHOENOLPYRUVATE. Several different isoforms of this enzyme exist, each with its own tissue specificity. (mesh:D010751)
| Synonym | Reference | Specificity |
| enolase | Exact |
| Identifier | Name | Relation |
| HGNC:3354 | ENO3 | isa |
| HGNC:31670 | ENO4 | isa |
| HGNC:3353 | ENO2 | isa |
| HGNC:3350 | ENO1 | isa |