ERK

A mitogen-activated protein kinase subfamily that is widely expressed and plays a role in regulation of MEIOSIS; MITOSIS; and post mitotic functions in differentiated cells. The extracellular signal regulated MAP kinases are regulated by a broad variety of CELL SURFACE RECEPTORS and can be activated by certain CARCINOGENS. (mesh:D048049)

Cross-references

• RE:R-HSA-2422450
• RE:R-HSA-5674338
• NCIT:C26360
• SFAM:F0134
• RE:R-HSA-5674340
• SIGNOR:SIGNOR-PF1
• MEDSCAN:urn:agi-aopfc:0000458
• BEL:MAPK Erk1/3 Family
• RE:R-HSA-5675361
• RE:R-HSA-169291
• RE:R-HSA-3656389
• RE:R-HSA-169289
• BEL:MAPK Erk1/2 Family
• RE:R-HSA-198701
• RE:R-HSA-5674341
• IP:IPR008349
• RE:R-HSA-5675363
• MESH:D048049 - Extracellular Signal-Regulated MAP Kinases
• RE:R-HSA-1268261

Synonyms

Synonym	Reference	Specificity
p42 and p38 MAPK		Exact
ERK 1/2		Exact
Erk		Exact
ERK-1/2		Exact
p42(mapk) and p44(mapk)		Exact
ERK		Exact
ERK mitogen-activated protein kinase		Exact
p42 and p38 MAP kinases		Exact
p42 and p44 MAPK		Exact
extracellular signal-regulated kinase		Exact
ERKs		Exact
Erk1/2		Exact
ERK MAPK		Exact
ERK1/2		Exact
p44 and p42		Exact
p42 and p44		Exact
p42 and p44MAP kinase		Exact
ERK1/2 MAPK		Exact
p42/44		Exact
p42 and p38 MAPKs		Exact
phospho-ERK1/2		Exact
Extracellular Signal Regulated Kinase		Exact

Incoming Relations

Identifier	Name	Relation
HGNC:6877	MAPK3	isa
HGNC:6871	MAPK1	isa

Outgoing Relations

Relation	Identifier	Name
isa	FPLX:MAPK	MAPK