A family of G-protein-coupled receptors that was originally identified by its ability to bind N-formyl peptides such as N-FORMYLMETHIONINE LEUCYL-PHENYLALANINE. Since N-formyl peptides are found in MITOCHONDRIA and BACTERIA, this class of receptors is believed to play a role in mediating cellular responses to cellular damage and bacterial invasion. However, non-formylated peptide ligands have also been found for this receptor class. (mesh:D044042)
Identifier | Name | Relation |
HGNC:3826 | FPR1 | isa |
HGNC:3827 | FPR2 | isa |
HGNC:3828 | FPR3 | isa |