FPR

A family of G-protein-coupled receptors that was originally identified by its ability to bind N-formyl peptides such as N-FORMYLMETHIONINE LEUCYL-PHENYLALANINE. Since N-formyl peptides are found in MITOCHONDRIA and BACTERIA, this class of receptors is believed to play a role in mediating cellular responses to cellular damage and bacterial invasion. However, non-formylated peptide ligands have also been found for this receptor class. (mesh:D044042)

Cross-references

Synonyms

None available.

Incoming Relations

Identifier Name Relation
HGNC:3827 FPR2 isa
HGNC:3826 FPR1 isa
HGNC:3828 FPR3 isa

Outgoing Relations

None available.