Fibrinogen

Plasma glycoprotein clotted by thrombin, composed of a dimer of three non-identical pairs of polypeptide chains (alpha, beta, gamma) held together by disulfide bonds. Fibrinogen clotting is a sol-gel change involving complex molecular arrangements: whereas fibrinogen is cleaved by thrombin to form polypeptides A and B, the proteolytic action of other enzymes yields different fibrinogen degradation products. (mesh:D005340)

Cross-references

• IP:IPR012290
• RE:R-HSA-114617
• GO:GO:0005577 - fibrinogen complex
• RE:R-HSA-114618
• RE:R-HSA-8870680
• RE:R-HSA-139933
• MESH:D005340 - Fibrinogen
• RE:R-HSA-140919
• BEL:Fibrinogen Complex
• RE:R-HSA-140586
• RE:R-HSA-139934
• SCOMP:C0052

Synonyms

Synonym	Reference	Specificity
fibrinogen		Exact

Incoming Relations

Identifier	Name	Relation
HGNC:3662	FGB	partof
HGNC:3694	FGG	partof
HGNC:3661	FGA	partof

Outgoing Relations

None available.