Plasma glycoprotein clotted by thrombin, composed of a dimer of three non-identical pairs of polypeptide chains (alpha, beta, gamma) held together by disulfide bonds. Fibrinogen clotting is a sol-gel change involving complex molecular arrangements: whereas fibrinogen is cleaved by thrombin to form polypeptides A and B, the proteolytic action of other enzymes yields different fibrinogen degradation products. (mesh:D005340)



Synonym Reference Specificity
fibrinogen Exact

Incoming Relations

Identifier Name Relation
HGNC:3661 FGA partof
HGNC:3662 FGB partof
HGNC:3694 FGG partof

Outgoing Relations

None available.