GABR
Cell-surface proteins that bind GAMMA-AMINOBUTYRIC ACID with high affinity and trigger changes that influence the behavior of cells. GABA-A receptors control chloride channels formed by the receptor complex itself. They are blocked by bicuculline and usually have modulatory sites sensitive to benzodiazepines and barbiturates. GABA-B receptors act through G-proteins on several effector systems, are insensitive to bicuculline, and have a high affinity for L-baclofen.
(mesh:D018079)
Cross-references
Synonyms
| Synonym |
Reference |
Specificity |
| GABA receptors |
|
Exact
|
| gamma-aminobutyric-acid A receptor |
|
Exact
|
| GABA receptor |
|
Exact
|
| GABA-A receptor |
|
Exact
|
| γ-aminobutyric-acid A receptor |
|
Exact
|
Incoming Relations
Outgoing Relations