GABR

Cell-surface proteins that bind GAMMA-AMINOBUTYRIC ACID with high affinity and trigger changes that influence the behavior of cells. GABA-A receptors control chloride channels formed by the receptor complex itself. They are blocked by bicuculline and usually have modulatory sites sensitive to benzodiazepines and barbiturates. GABA-B receptors act through G-proteins on several effector systems, are insensitive to bicuculline, and have a high affinity for L-baclofen. (mesh:D018079)

Cross-references

Synonyms

Synonym Reference Specificity
γ-aminobutyric-acid A receptor Exact
GABA receptors Exact
GABA receptor Exact
gamma-aminobutyric-acid A receptor Exact
GABA-A receptor Exact

Incoming Relations

Identifier Name Relation
HGNC:4075 GABRA1 isa
HGNC:4090 GABRR1 isa
HGNC:4087 GABRG2 isa
HGNC:4084 GABRD isa
HGNC:4089 GABRP isa
HGNC:4091 GABRR2 isa
HGNC:4085 GABRE isa
HGNC:4078 GABRA4 isa
HGNC:4076 GABRA2 isa
HGNC:4080 GABRA6 isa
HGNC:17969 GABRR3 isa
HGNC:4086 GABRG1 isa
HGNC:4077 GABRA3 isa
HGNC:4079 GABRA5 isa
HGNC:4081 GABRB1 isa
HGNC:4082 GABRB2 isa
HGNC:4083 GABRB3 isa
HGNC:4088 GABRG3 isa
HGNC:14454 GABRQ isa

Outgoing Relations

Relation Identifier Name
isa FPLX:Ligand_gated_ion_channels Ligand_gated_ion_channels