An enzyme that catalyzes the conversion of GTP to 3',5'-cyclic GMP and pyrophosphate. It also acts on ITP and dGTP. (From Enzyme Nomenclature, 1992) EC 4.6.1.2. (mesh:D006162)
| Synonym | Reference | Specificity |
| guanylate cyclase | Exact | |
| guanylyl cyclase | Exact |
| Identifier | Name | Relation |
| HGNC:7944 | NPR2 | isa |
| HGNC:4689 | GUCY2D | isa |
| HGNC:4691 | GUCY2F | isa |
| HGNC:4688 | GUCY2C | isa |
| HGNC:7943 | NPR1 | isa |