G_alpha

The GTPase-containing subunits of heterotrimeric GTP-binding proteins. When dissociated from the heterotrimeric complex these subunits interact with a variety of second messenger systems. Hydrolysis of GTP by the inherent GTPase activity of the subunit causes it to revert to its inactive (heterotrimeric) form. The GTP-Binding protein alpha subunits are grouped into families according to the type of action they have on second messenger systems. (mesh:D044385)

Cross-references

• MESH:D044385 - GTP-Binding Protein alpha Subunits
• PF:PF00503

Synonyms

Synonym	Reference	Specificity
G protein alpha		Exact
Galpha		Exact
G alpha		Exact
G-protein alpha		Exact
G-α		Exact
G-alpha		Exact

Incoming Relations

Identifier	Name	Relation
FPLX:G_12_alpha	G_12_alpha	isa
FPLX:G_s_alpha	G_s_alpha	isa
FPLX:G_i_alpha	G_i_alpha	isa
FPLX:G_q_alpha	G_q_alpha	isa

Outgoing Relations

None available.