The GTPase-containing subunits of heterotrimeric GTP-binding proteins. When dissociated from the heterotrimeric complex these subunits interact with a variety of second messenger systems. Hydrolysis of GTP by the inherent GTPase activity of the subunit causes it to revert to its inactive (heterotrimeric) form. The GTP-Binding protein alpha subunits are grouped into families according to the type of action they have on second messenger systems. (mesh:D044385)



Synonym Reference Specificity
G alpha Exact
G-protein alpha Exact
G-α Exact
G-alpha Exact
G protein alpha Exact
Galpha Exact

Incoming Relations

Identifier Name Relation
FPLX:G_i_alpha G_i_alpha isa
FPLX:G_q_alpha G_q_alpha isa
FPLX:G_s_alpha G_s_alpha isa
FPLX:G_12_alpha G_12_alpha isa

Outgoing Relations

None available.