A family of heterotrimeric GTP-binding protein alpha subunits that were originally identified by their ability to inhibit ADENYLYL CYCLASES. Members of this family can couple to beta and gamma G-protein subunits that activate POTASSIUM CHANNELS. The Gi-Go part of the name is also spelled Gi/Go. (mesh:D019206)



Synonym Reference Specificity
G-Protein alpha-i Exact
Gi alpha subunit Exact
Gi α subunit Exact
Gi α Exact
Gi alpha Exact
G alphai Exact
Gαi Exact
Galphai Exact
G αi Exact
G-Protein α-i Exact

Incoming Relations

Identifier Name Relation
HGNC:4395 GNAZ isa
HGNC:4394 GNAT2 isa
HGNC:4384 GNAI1 isa
HGNC:22800 GNAT3 isa
HGNC:4393 GNAT1 isa
HGNC:4385 GNAI2 isa
HGNC:4387 GNAI3 isa
HGNC:4389 GNAO1 isa

Outgoing Relations

Relation Identifier Name
partof FPLX:G_i G_i
isa FPLX:G_alpha G_alpha