HDAC

Deacetylases that remove N-acetyl groups from amino side chains of the amino acids of HISTONES. The enzyme family can be divided into at least three structurally-defined subclasses. Class I and class II deacetylases utilize a zinc-dependent mechanism. The sirtuin histone deacetylases belong to class III and are NAD-dependent enzymes. (mesh:D006655)

Cross-references

Synonyms

Synonym Reference Specificity
histone deacetylase Exact
histone deacetylases Exact
HDAC Exact

Incoming Relations

Identifier Name Relation
FPLX:HDAC_I HDAC_I isa
FPLX:HDAC_III HDAC_III isa
FPLX:HDAC_IV HDAC_IV isa
FPLX:HDAC_II HDAC_II isa

Outgoing Relations

None available.