HDL

A class of lipoproteins of small size (4-13 nm) and dense (greater than 1.063 g/ml) particles. HDL lipoproteins, synthesized in the liver without a lipid core, accumulate cholesterol esters from peripheral tissues and transport them to the liver for re-utilization or elimination from the body (the reverse cholesterol transport). Their major protein component is APOLIPOPROTEIN A-I. HDL also shuttle APOLIPOPROTEINS C and APOLIPOPROTEINS E to and from triglyceride-rich lipoproteins during their catabolism. HDL plasma level has been inversely correlated with the risk of cardiovascular diseases. (mesh:D008075)

Cross-references

• NCIT:C25186
• MESH:D008075 - Lipoproteins, HDL
• BEL:HDL Complex
• SCOMP:C0059
• GO:GO:0034364 - high-density lipoprotein particle

Synonyms

Synonym	Reference	Specificity
HDL		Exact
High-density lipoproteins		Exact

Incoming Relations

Identifier	Name	Relation
HGNC:613	APOE	partof
HGNC:600	APOA1	partof
HGNC:601	APOA2	partof
HGNC:2095	CLU	partof
HGNC:399	ALB	partof

Outgoing Relations

None available.