A class of lipoproteins of small size (4-13 nm) and dense (greater than 1.063 g/ml) particles. HDL lipoproteins, synthesized in the liver without a lipid core, accumulate cholesterol esters from peripheral tissues and transport them to the liver for re-utilization or elimination from the body (the reverse cholesterol transport). Their major protein component is APOLIPOPROTEIN A-I. HDL also shuttle APOLIPOPROTEINS C and APOLIPOPROTEINS E to and from triglyceride-rich lipoproteins during their catabolism. HDL plasma level has been inversely correlated with the risk of cardiovascular diseases. (mesh:D008075)



Synonym Reference Specificity
HDL Exact
High-density lipoproteins Exact

Incoming Relations

Identifier Name Relation
HGNC:600 APOA1 partof
HGNC:2095 CLU partof
HGNC:399 ALB partof
HGNC:601 APOA2 partof
HGNC:613 APOE partof

Outgoing Relations

None available.