A mixed function oxidase enzyme which during hemoglobin catabolism catalyzes the degradation of heme to ferrous iron, carbon monoxide and biliverdin in the presence of molecular oxygen and reduced NADPH. The enzyme is induced by metals, particularly cobalt. (mesh:D006419)



Synonym Reference Specificity
heme oxygenase Exact
haem oxygenase Exact

Incoming Relations

Identifier Name Relation
HGNC:5014 HMOX2 isa
HGNC:5013 HMOX1 isa

Outgoing Relations

None available.