One of the type I interferons produced by peripheral blood leukocytes or lymphoblastoid cells. In addition to antiviral activity, it activates NATURAL KILLER CELLS and B-LYMPHOCYTES, and down-regulates VASCULAR ENDOTHELIAL GROWTH FACTOR expression through PI-3 KINASE and MAPK KINASES signaling pathways. (mesh:D016898)
| Synonym | Reference | Specificity |
| IFNalpha | Exact | |
| IFN-alpha | Exact | |
| IFN-a | Exact | |
| IFNα | Exact | |
| IFN-α | Exact |
| Identifier | Name | Relation |
| HGNC:5426 | IFNA5 | isa |
| HGNC:5421 | IFNA16 | isa |
| HGNC:5427 | IFNA6 | isa |
| HGNC:5428 | IFNA7 | isa |
| HGNC:5424 | IFNA21 | isa |
| HGNC:5425 | IFNA4 | isa |
| HGNC:5422 | IFNA17 | isa |
| HGNC:5419 | IFNA13 | isa |
| HGNC:5423 | IFNA2 | isa |
| HGNC:5417 | IFNA1 | isa |
| HGNC:5429 | IFNA8 | isa |
| HGNC:5418 | IFNA10 | isa |
| HGNC:5420 | IFNA14 | isa |
| Relation | Identifier | Name |
| isa | FPLX:Interferon | Interferon |