One of the type I interferons produced by peripheral blood leukocytes or lymphoblastoid cells. In addition to antiviral activity, it activates NATURAL KILLER CELLS and B-LYMPHOCYTES, and down-regulates VASCULAR ENDOTHELIAL GROWTH FACTOR expression through PI-3 KINASE and MAPK KINASES signaling pathways. (mesh:D016898)



Synonym Reference Specificity
IFN-alpha Exact
IFN-a Exact
IFN-α Exact
IFNα Exact
IFNalpha Exact

Incoming Relations

Identifier Name Relation
HGNC:5419 IFNA13 isa
HGNC:5424 IFNA21 isa
HGNC:5423 IFNA2 isa
HGNC:5426 IFNA5 isa
HGNC:5428 IFNA7 isa
HGNC:5425 IFNA4 isa
HGNC:5418 IFNA10 isa
HGNC:5421 IFNA16 isa
HGNC:5417 IFNA1 isa
HGNC:5429 IFNA8 isa
HGNC:5420 IFNA14 isa
HGNC:5427 IFNA6 isa
HGNC:5422 IFNA17 isa

Outgoing Relations

Relation Identifier Name
isa FPLX:Interferon Interferon