IFNAR

A ubiquitously expressed heterodimeric receptor that is specific for both INTERFERON-ALPHA and INTERFERON-BETA. It is composed of two subunits referred to as IFNAR1 and IFNAR2. The IFNAR2 subunit is believed to serve as the ligand-binding chain; however both chains are required for signal transduction. The interferon alpha-beta receptor signals through the action of JANUS KINASES such as the TYK2 KINASE. (mesh:D053633)

Cross-references

Synonyms

Synonym Reference Specificity
Interferon-alpha/beta receptor Exact
Ifnar Exact
interferon-α/β receptor Exact
IFNAR Exact

Incoming Relations

Identifier Name Relation
HGNC:5432 IFNAR1 isa
HGNC:5433 IFNAR2 isa

Outgoing Relations

None available.