A family of inhibitory proteins which bind to the REL PROTO-ONCOGENE PROTEINS and modulate their activity. In the CYTOPLASM, I-kappa B proteins bind to the transcription factor NF-KAPPA B. Cell stimulation causes its dissociation and translocation of active NF-kappa B to the nucleus. (mesh:D020672)



None available.

Incoming Relations

Identifier Name Relation
HGNC:5960 IKBKB isa
HGNC:1974 CHUK isa
HGNC:14552 IKBKE isa
HGNC:5961 IKBKG isa
HGNC:11584 TBK1 isa

Outgoing Relations

None available.