IL1

A soluble factor produced by MONOCYTES; MACROPHAGES, and other cells which activates T-lymphocytes and potentiates their response to mitogens or antigens. Interleukin-1 is a general term refers to either of the two distinct proteins, INTERLEUKIN-1ALPHA and INTERLEUKIN-1BETA. The biological effects of IL-1 include the ability to replace macrophage requirements for T-cell activation. (mesh:D007375)

Cross-references

• SFAM:F0125
• BEL:IL1 Family
• NXP:FA:01820
• MEDSCAN:urn:agi-aopfc:0000615
• NCIT:C20506
• IP:IPR003502
• RE:R-HSA-445744
• MESH:D007375 - Interleukin-1
• PF:PF00340

Synonyms

Synonym	Reference	Specificity
IL-1		Exact
IL1 family		Exact

Incoming Relations

Identifier	Name	Relation
HGNC:5992	IL1B	isa
HGNC:5991	IL1A	isa

Outgoing Relations

None available.