A soluble factor produced by MONOCYTES; MACROPHAGES, and other cells which activates T-lymphocytes and potentiates their response to mitogens or antigens. Interleukin-1 is a general term refers to either of the two distinct proteins, INTERLEUKIN-1ALPHA and INTERLEUKIN-1BETA. The biological effects of IL-1 include the ability to replace macrophage requirements for T-cell activation. (mesh:D007375)



Synonym Reference Specificity
IL1 family Exact
IL-1 Exact

Incoming Relations

Identifier Name Relation
HGNC:5991 IL1A isa
HGNC:5992 IL1B isa

Outgoing Relations

None available.