IL12

A heterodimeric cytokine that plays a role in innate and adaptive immune responses. Interleukin-12 is a 70 kDa protein that is composed of covalently linked 40 kDa and 35 kDa subunits. It is produced by DENDRITIC CELLS; MACROPHAGES and a variety of other immune cells and plays a role in the stimulation of INTERFERON-GAMMA production by T-LYMPHOCYTES and NATURAL KILLER CELLS. (mesh:D018664)

Cross-references

• RE:R-HSA-8950122
• NCIT:C20514
• RE:R-HSA-447102
• RE:R-HSA-8950228
• RE:R-HSA-8950694
• MESH:D018664 - Interleukin-12
• PF:PF03039
• MEDSCAN:urn:agi-complex:IL12

Synonyms

Synonym	Reference	Specificity
IL-12		Exact
IL12		Exact

Incoming Relations

Identifier	Name	Relation
HGNC:5969	IL12A	isa
HGNC:5970	IL12B	isa

Outgoing Relations

None available.