A heterodimeric cytokine that plays a role in innate and adaptive immune responses. Interleukin-12 is a 70 kDa protein that is composed of covalently linked 40 kDa and 35 kDa subunits. It is produced by DENDRITIC CELLS; MACROPHAGES and a variety of other immune cells and plays a role in the stimulation of INTERFERON-GAMMA production by T-LYMPHOCYTES and NATURAL KILLER CELLS. (mesh:D018664)



Synonym Reference Specificity
IL12 Exact
IL-12 Exact

Incoming Relations

Identifier Name Relation
HGNC:5970 IL12B isa
HGNC:5969 IL12A isa

Outgoing Relations

None available.