ITGA2B1

An integrin found on fibroblasts, platelets, endothelial and epithelial cells, and lymphocytes where it functions as a receptor for COLLAGEN and LAMININ. Although originally referred to as the collagen receptor, it is one of several receptors for collagen. Ligand binding to integrin alpha2beta1 triggers a cascade of intracellular signaling, including activation of p38 MAP kinase. (mesh:D038982)

Cross-references

• MESH:D038982 - Integrin alpha2beta1
• SIGNOR:SIGNOR-C160

Synonyms

Synonym	Reference	Specificity
alpha2beta1 integrin		Exact

Incoming Relations

Identifier	Name	Relation
HGNC:6153	ITGB1	partof
HGNC:6137	ITGA2	partof

Outgoing Relations

Relation	Identifier	Name
isa	FPLX:Integrins	Integrins