ITGB

Integrin beta chains combine with integrin alpha chains to form heterodimeric cell surface receptors. Integrins have traditionally been classified into functional groups based on the identity of one of three beta chains present in the heterodimer. The beta chain is necessary and sufficient for integrin-dependent signaling. Its short cytoplasmic tail contains sequences critical for inside-out signaling. (mesh:D039641)

Cross-references

• HGNC_GROUP:1159
• MESH:D039641 - Integrin beta Chains

Synonyms

None available.

Incoming Relations

Identifier	Name	Relation
HGNC:6164	ITGBL1	isa
HGNC:6163	ITGB8	isa
HGNC:6156	ITGB3	isa
HGNC:6158	ITGB4	isa
HGNC:6162	ITGB7	isa
HGNC:6161	ITGB6	isa
HGNC:6153	ITGB1	isa
HGNC:6160	ITGB5	isa
HGNC:6155	ITGB2	isa

Outgoing Relations

Relation	Identifier	Name
isa	FPLX:Integrins	Integrins