Intracellular receptors that bind to INOSITOL 1,4,5-TRISPHOSPHATE and play an important role in its intracellular signaling. Inositol 1,4,5-trisphosphate receptors are calcium channels that release CALCIUM in response to increased levels of inositol 1,4,5-trisphosphate in the CYTOPLASM. (mesh:D053496)



None available.

Incoming Relations

Identifier Name Relation
HGNC:6182 ITPR3 isa
HGNC:6181 ITPR2 isa
HGNC:6180 ITPR1 isa

Outgoing Relations

Relation Identifier Name
isa FPLX:Calcium_channels Calcium_channels
isa FPLX:Ligand_gated_ion_channels Ligand_gated_ion_channels