KLK

Proteolytic enzymes from the serine endopeptidase family found in normal blood and urine. Specifically, Kallikreins are potent vasodilators and hypotensives and increase vascular permeability and affect smooth muscle. They act as infertility agents in men. Three forms are recognized, PLASMA KALLIKREIN (EC 3.4.21.34), TISSUE KALLIKREIN (EC 3.4.21.35), and PROSTATE-SPECIFIC ANTIGEN (EC 3.4.21.77). (mesh:D007610)

Cross-references

Synonyms

Synonym Reference Specificity
KLKs Exact
tissue kallikreins Exact
kallikrein Exact
tissue kallikrein Exact
kallikrein-related peptidases Exact

Incoming Relations

Identifier Name Relation
HGNC:6366 KLK5 isa
HGNC:6362 KLK14 isa
HGNC:6365 KLK4 isa
HGNC:6369 KLK8 isa
HGNC:20453 KLK15 isa
HGNC:6358 KLK10 isa
HGNC:6360 KLK12 isa
HGNC:6361 KLK13 isa
HGNC:6357 KLK1 isa
HGNC:6363 KLK2 isa
HGNC:6371 KLKB1 isa
HGNC:6367 KLK6 isa
HGNC:6359 KLK11 isa
HGNC:6368 KLK7 isa
HGNC:6364 KLK3 isa
HGNC:6370 KLK9 isa

Outgoing Relations

None available.