An adhesion-promoting leukocyte surface membrane heterodimer. The alpha subunit consists of the CD11b ANTIGEN and the beta subunit the CD18 ANTIGEN. The antigen, which is an integrin, functions both as a receptor for complement 3 and in cell-cell and cell-substrate adhesive interactions. (mesh:D016177)
| Synonym | Reference | Specificity |
| MAC-1 | Exact |
| Identifier | Name | Relation |
| HGNC:6155 | ITGB2 | partof |
| HGNC:6149 | ITGAM | partof |
| Relation | Identifier | Name |
| isa | FPLX:Integrins | Integrins |