MAP2K

A serine-threonine protein kinase family whose members are components in protein kinase cascades activated by diverse stimuli. These MAPK kinases phosphorylate MITOGEN-ACTIVATED PROTEIN KINASES and are themselves phosphorylated by MAP KINASE KINASE KINASES. JNK kinases (also known as SAPK kinases) are a subfamily. (mesh:D020929)

Cross-references

Synonyms

Synonym Reference Specificity
MKKs Exact
MAPK kinase Exact
mitogen-activated protein kinase kinase Exact

Incoming Relations

Identifier Name Relation
FPLX:MEK MEK isa
HGNC:6846 MAP2K6 isa
HGNC:6844 MAP2K4 isa
HGNC:6845 MAP2K5 isa
HGNC:6843 MAP2K3 isa
HGNC:6847 MAP2K7 isa

Outgoing Relations

None available.