MAP2K

A serine-threonine protein kinase family whose members are components in protein kinase cascades activated by diverse stimuli. These MAPK kinases phosphorylate MITOGEN-ACTIVATED PROTEIN KINASES and are themselves phosphorylated by MAP KINASE KINASE KINASES. JNK kinases (also known as SAPK kinases) are a subfamily. (mesh:D020929)

Cross-references

• MESH:D020929 - Mitogen-Activated Protein Kinase Kinases
• NCIT:C105947

Synonyms

Synonym	Reference	Specificity
MKKs		Exact
MAPK kinase		Exact
mitogen-activated protein kinase kinase		Exact

Incoming Relations

Identifier	Name	Relation
FPLX:MEK	MEK	isa
HGNC:6846	MAP2K6	isa
HGNC:6844	MAP2K4	isa
HGNC:6845	MAP2K5	isa
HGNC:6843	MAP2K3	isa
HGNC:6847	MAP2K7	isa

Outgoing Relations

None available.