MAPK

A superfamily of PROTEIN-SERINE-THREONINE KINASES that are activated by diverse stimuli via protein kinase cascades. They are the final components of the cascades, activated by phosphorylation by MITOGEN-ACTIVATED PROTEIN KINASE KINASES, which in turn are activated by mitogen-activated protein kinase kinase kinases (MAP KINASE KINASE KINASES). (mesh:D020928)

Cross-references

• ECCODE:2.7.11.24 - Mitogen-activated protein kinase
• NCIT:C16376
• ECCODE:2.7.12.2 - Mitogen-activated protein kinase kinase
• MESH:D020928 - Mitogen-Activated Protein Kinases

Synonyms

Synonym	Reference	Specificity
mitogen-activated protein kinases		Exact
mitogen activated protein kinase		Exact
MAP kinase		Exact
MAPKs		Exact
MAPK		Exact
mitogen-activated protein kinase		Exact
MAP kinases		Exact
mitogen activated protein kinases		Exact

Incoming Relations

Identifier	Name	Relation
FPLX:ERK	ERK	isa
FPLX:JNK	JNK	isa
FPLX:p38	p38	isa

Outgoing Relations

None available.