Notch

A family of conserved cell surface receptors that contain EPIDERMAL GROWTH FACTOR repeats in their extracellular domain and ANKYRIN REPEATS in their cytoplasmic domains. The cytoplasmic domains are released upon ligand binding and translocate to the CELL NUCLEUS, where they act as transcription factors. (mesh:D051880)

Cross-references

Synonyms

Synonym Reference Specificity
NOTCH Exact
Notch Exact

Incoming Relations

Identifier Name Relation
HGNC:7882 NOTCH2 isa
HGNC:7884 NOTCH4 isa
HGNC:7881 NOTCH1 isa
HGNC:7883 NOTCH3 isa

Outgoing Relations

None available.