The OTU (ovarian tumor protease) family is a family of deubiquitinating enzymes characterized by the presence of a OTU domain, which is a conserved catalytic domain. OTU enzymes are cysteine proteases.
| Identifier | Name | Relation |
| FPLX:OTUB | OTUB | isa |
| HGNC:25118 | OTULIN | isa |
| HGNC:25629 | OTULINL | isa |
| FPLX:OTUD | OTUD | isa |
| HGNC:30897 | VCPIP1 | isa |
| HGNC:30881 | ALG13 | isa |
| HGNC:18224 | ZRANB1 | isa |
| Relation | Identifier | Name |
| isa | FPLX:Deubiquitinase | Deubiquitinase |