P70S6K

A family of ribosomal protein S6 kinases that are considered the major physiological kinases for RIBOSOMAL PROTEIN S6. Unlike RIBOSOMAL PROTEIN S6 KINASES, 90KDa the proteins in this family are sensitive to the inhibitory effects of RAPAMYCIN and contain a single kinase domain. They are referred to as 70kDa proteins, however ALTERNATIVE SPLICING of mRNAs for proteins in this class also results in 85kDa variants being formed. (mesh:D038762)

Cross-references

Synonyms

Synonym Reference Specificity
P70S6K Exact
p70RSK Exact
S6K Exact
P70RSK Exact
s6k Exact
p70 S6 kinase Exact

Incoming Relations

Identifier Name Relation
HGNC:10436 RPS6KB1 isa
HGNC:10437 RPS6KB2 isa

Outgoing Relations

Relation Identifier Name
isa FPLX:RSK RSK