A family of serine-threonine kinases that bind to and are activated by MONOMERIC GTP-BINDING PROTEINS such as RAC GTP-BINDING PROTEINS and CDC42 GTP-BINDING PROTEIN. They are intracellular signaling kinases that play a role the regulation of cytoskeletal organization. (mesh:D054462)
Synonym | Reference | Specificity |
Pak | Exact | |
PAK | Exact |
Identifier | Name | Relation |
HGNC:15916 | PAK5 | isa |
HGNC:8591 | PAK2 | isa |
HGNC:16061 | PAK6 | isa |
HGNC:8592 | PAK3 | isa |
HGNC:16059 | PAK4 | isa |
HGNC:8590 | PAK1 | isa |