A family of serine-threonine kinases that bind to and are activated by MONOMERIC GTP-BINDING PROTEINS such as RAC GTP-BINDING PROTEINS and CDC42 GTP-BINDING PROTEIN. They are intracellular signaling kinases that play a role the regulation of cytoskeletal organization. (mesh:D054462)



Synonym Reference Specificity
PAK Exact
Pak Exact

Incoming Relations

Identifier Name Relation
HGNC:16061 PAK6 isa
HGNC:15916 PAK5 isa
HGNC:8591 PAK2 isa
HGNC:8590 PAK1 isa
HGNC:16059 PAK4 isa
HGNC:8592 PAK3 isa

Outgoing Relations

None available.