A class of enzymes that catalyze the hydrolysis of one of the two ester bonds in a phosphodiester compound. EC 3.1.4. (mesh:D010727)
| Synonym | Reference | Specificity |
| phosphodiesterases | Exact | |
| PDEs | Exact | |
| PDE | Exact | |
| Phosphodiesterases | Exact | |
| Phosphodiesterase | Exact | |
| phosphodiesterase | Exact |
| Identifier | Name | Relation |
| FPLX:PDE8 | PDE8 | isa |
| FPLX:PDE1 | PDE1 | isa |
| FPLX:PDE4 | PDE4 | isa |
| HGNC:8777 | PDE2A | isa |
| HGNC:8772 | PDE10A | isa |
| HGNC:8773 | PDE11A | isa |
| FPLX:PDE6 | PDE6 | isa |
| FPLX:PDE3 | PDE3 | isa |
| FPLX:PDE7 | PDE7 | isa |
| HGNC:8795 | PDE9A | isa |