PDGFR

Specific receptors on cell membranes that react with PLATELET-DERIVED GROWTH FACTOR, its analogs, or antagonists. The alpha PDGF receptor (RECEPTOR, PLATELET-DERIVED GROWTH FACTOR ALPHA) and the beta PDGF receptor (RECEPTOR, PLATELET-DERIVED GROWTH FACTOR BETA) are the two principle types of PDGF receptors. Activation of the protein-tyrosine kinase activity of the receptors occurs by ligand-induced dimerization or heterodimerization of PDGF receptor types. (mesh:D017479)

Cross-references

• RE:R-HSA-186821
• RE:R-HSA-186770
• RE:R-HSA-8864040
• SFAM:F0170
• NCIT:C17322
• MESH:D017479 - Receptors, Platelet-Derived Growth Factor
• RE:R-HSA-186791
• RE:R-HSA-186769
• RE:R-HSA-186792
• BEL:PDGFR Family

Synonyms

Synonym	Reference	Specificity
derived growth factor		Exact
PDGFR		Exact
PDGF receptors		Exact

Incoming Relations

Identifier	Name	Relation
HGNC:8803	PDGFRA	isa
HGNC:8804	PDGFRB	isa

Outgoing Relations

None available.