PDGFR

Specific receptors on cell membranes that react with PLATELET-DERIVED GROWTH FACTOR, its analogs, or antagonists. The alpha PDGF receptor (RECEPTOR, PLATELET-DERIVED GROWTH FACTOR ALPHA) and the beta PDGF receptor (RECEPTOR, PLATELET-DERIVED GROWTH FACTOR BETA) are the two principle types of PDGF receptors. Activation of the protein-tyrosine kinase activity of the receptors occurs by ligand-induced dimerization or heterodimerization of PDGF receptor types. (mesh:D017479)

Cross-references

Synonyms

Synonym Reference Specificity
PDGF receptors Exact
derived growth factor Exact
PDGFR Exact

Incoming Relations

Identifier Name Relation
HGNC:8803 PDGFRA isa
HGNC:8804 PDGFRB isa

Outgoing Relations

None available.