PLC

A subclass of phospholipases that hydrolyze the phosphoester bond found in the third position of GLYCEROPHOSPHOLIPIDS. Although the singular term phospholipase C specifically refers to an enzyme that catalyzes the hydrolysis of PHOSPHATIDYLCHOLINE (EC 3.1.4.3), it is commonly used in the literature to refer to broad variety of enzymes that specifically catalyze the hydrolysis of PHOSPHATIDYLINOSITOLS. (mesh:D010738)

Cross-references

• BEL:PLC Family
• MESH:D010738 - Type C Phospholipases
• SFAM:F0178

Synonyms

Synonym	Reference	Specificity
Phospholipase C		Exact
Phospholipase-C		Exact
phospholipase-C		Exact
PLC		Exact
phospholipase C		Exact

Incoming Relations

Identifier	Name	Relation
FPLX:PLCB	PLCB	isa
HGNC:17175	PLCE1	isa
HGNC:19218	PLCZ1	isa
FPLX:PLCG	PLCG	isa
FPLX:PLCD	PLCD	isa

Outgoing Relations

None available.